Kehitysvammahuollon tietopankki
 | Kirjaesittely |
Lubec, Gert: The Molecular Biology of Down Syndrome (Journal of Neural
Transmission, 57). New York: NY: Springer-Verlag 1999
Product Description:
This book contains updated reviews and original research work on Down Syndrome
focussing on brandnew results in neurobiology, in particular results on gene
hunting (subtractive hybridization, differential display) and neurochemistry.
The book provides new data such as a subtractive library of Down Syndrome brain
showing cDNAs that are overexpressed or downregulated and can be regarded as a
source for further research on the preliminary transcriptional data given. A
2D-electrophoretic map of human brain proteins including Down Syndrome brain
protein expression established by in-gel-digestion of spots with subsequent
MALDI-identification provides the scientific basis for protein work to the
neuroscientist. Altogether, the book provides a series of new candidate genes
possibly involved in Down Syndrome neurobiology, tools for neuroscience studies
on Down Syndrome brain thus serving as a manual and updated views and aspects on
Down Syndrome pathobiology.
Linkkejä:
Kehitysvamma-alan kirjallisuutta10.3.2005